iron Archives - Science Connected Magazine

Stopping Bacteria from Stealing Our Iron

June 22, 2017June 24, 2017 Science Connectedantibiotics, antimicrobial, iron, microbiology, siderophore, spinach

By Ada Hagan @adahagan As we discussed last time, bacteria that infect the human body face a major challenge, iron, which is essential for bacterial growth, is hard to obtain from human tissues. Many pathogenic bacteria solve this problem by deploying “stealth siderophores,” which steal iron from human iron-binding proteins while evading our defenses. In the battle between humans and pathogenic bacteria, our best weapons—antibiotics—are being weakened by widespread resistance. Is there a way to use bacteria’s need for iron against them? Researchers have pursued the answer to this question…

Biology Health

Spinach and Siderophores: The Bacterial Battle for Iron

June 15, 2017June 22, 2017 Science Connectedbiology, iron, microbiology, siderophore, spinach, transferrin

By Ada Hagan @adahagan Many remember the boisterous, muscle-bound, tattooed sailor Popeye and the thin-as-a-rail Olive Oyl from Saturday morning cartoons. In times of need, such as when his rival Bluto abducted Olive Oyl for the 50th time, Popeye would squeeze open a tin can of spinach. Eating the spinach, sometimes miraculously through his corn-cob pipe, gave Popeye that extra boost of energy needed to escape his bonds and rescue Olive Oyl. What was so special about spinach that gave Popeye his superpower? Iron. Or so I thought. It’s popularly…